Extra work and frustration can be avoided by reclassifying troublesome regions.
Here are some examples of reclassification that may help resolve region problems:
Very small or narrow regions can often be fitted by planes.
Closed regions can often be fitted as cylinders, cones, revolved, or sweep/lofts.
If a closed freeform region (band, tube, etc.) is not "cone-projectable" meaning it is able to be mapped onto a conical shape without self-intersections or reclassified (extrusion, drafted extrude, loft, etc.) editing the contours and subdividing the region is your only option.
Classifying slightly "curved" planar regions or "distorted" cylinders to closed freeforms can also solve some troublesome areas.
Use the Edit Regions to keep the regions clean and avoid any problem areas.
Remove erroneous or unwanted data from the surface fitting calculations by "ignoring" data. Start with the Ignored Area Sensitivity slider. Then fine tune the data by "ignoring" (Ctrl-mouse select) or "adding" (mouse select) additional polygons as needed. Data inside the region such as noise, embossing, and labels, can also be removed in this manner.
Add more data in narrow or acute corners by using Refine or Rewrap in polygon mode if needed.
The regional dataset should reflect the changes made to your contour separator information from the last section. If you see major discrepancies between the regional and separator data, such as overlapping, clean this up before moving on.